Therapeutic Strategies in Lipid Disorders

AM Tonkin

Therapeutic Strategies in Lipid Disorders
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Product details

Published27th April 2009
ISBN9781846926013
Price£62.49
Print ISBN9781846920349
eISBN9781846926013
Author
PublisherClinical Publishing
Pages282
LanguageEnglish
Subjects:Cardiovascular medicine, Endocrinology
BIC:MJD, MJG
123Library ID:1866
Format:eBook

eBook Overview

Lipid disorders are now recognised as a diverse group of diseases that together represent one of the foremost risk factors for cardiovascular disease in general. Frequently present in association with other chronic illnesses such as hypertension, diabetes, and obesity, lipid disorders are a key therapeutic target for clinicians. This book examines the causes and consequences of lipid disorders, and the treatments available. Special chapters are dedicated to the associations between lipid disorders and other conditions, for example cerebrovascular disease and heart failure, as well as the wider applications for lipid-lowering agents in the management of co-morbidities. The book concludes with a review of novel lipid-modifying agents, emerging diagnostic technologies such as intravascular ultrasound, and the use of biomarkers as risk predictors.

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Table of Contents

Contents4
Editorand Contributors
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6
Foreword
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9
Chapter 1: A global view of cardiovascular risk factors
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10
Chapter 2: Low-density lipoprotein cholesterol as a therapeutic target
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23
Chapter 3: High-density lipoprotein as a therapeutic target
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36
Chapter 4: Apolipoprotein B in the therapy of atherogenic dyslipoproteinaemias
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49
Chapter 5: Management of coronary heart disease patients
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64
Chapter 6: Stroke and transient ischaemic attack prevention
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81
Chapter 7: Diabetes and the metabolic syndrome
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90
Chapter 8: Hypertension
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109
Chapter 9: Treatment of familial hypercholesterolaemia
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119
Chapter 10: Lipid lowering in chronic kidney disease
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137
Chapter 11: Statins and heart failure
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145
Chapter 12: Absolute risk assessment in the general population
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157
Chapter 13: Pleiotropic effects of statins and potential new indications
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179
Chapter 14: The role of imaging endpoints in clinical trials
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197
Chapter 15: Biomarkers in cardiovascular disease
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212
Chapter 16: Novel lipid-modifying agents
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227
Chapter 17: The enhanced evidence base and translation into improved outcomes
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245
Abbreviations262
Index269